The Creation of Adam by Michelangelo:
This is one of the most iconic and most widely recognized images of hands. It is located on the ceiling of the Sistine Chapel in the Vatican painted by Michelangelo between 1508 and 1512.

A series of nine panels create the fresco illustrating scenes from the Book of Genesis. The Creation of Adam is the best known and although fourth in the series of nine, it was among the last to be created circa 1511.

The hand of God is on the right. The hand of Adam is on the left.